Publications

Abstracts

E Clark, C Wood, A Tindell, K Graham, A McIntosh, F Morton and D Porter. Unmet need in early rheumatoid arthritis – why do some patients do badly despite modern treat-to-target strategies of care? Results from the Scottish Early RA (SERA) inception cohort. https://acrabstracts.org/abstract/unmet-need-in-early-rheumatoid-arthritis-why-do-some-patients-do-badly-despite-modern-treat-to-target-strategies-of-care-results-from-the-scottish-early-ra-sera-inception-cohort/

D Porter, F Morton, S Jain. Increase rates of bacterial infection in patients with ‘pre-RA’ (submitted 2022)

Papers

  1. Fragoulis G et al, Depression and anxiety in an Early Rheumatoid Arthritis inception cohort. Associations with demographic, socioeconomic and disease features. RMD Open 2020;6:e001376. doi: 10.1136/rmdopen-2020-001376
  • Ann Morgan, John Taylor, Tim Bongartz, et al, Genome-wide Association Study of Response to Methotrexate in Early Rheumatoid Arthritis Patients. The Pharmacogenomics Journal 2018 http://doi.org/10.1038/s41397-018-0025-5
  • Gabrielle Simoneau, Erica E. M. Moodie, Jagtar S. Nijjar, Robert W. Platt & the Scottish Early Rheumatoid Arthritis Inception Cohort Investigators (2019) Estimating Optimal Dynamic Treatment Regimes With Survival Outcomes, Journal of the American Statistical Association, DOI: 10.1080/01621459.2019.1629939
  • Fragoulis GE, Paterson C, Gilmour A, et al. Neutropaenia in early rheumatoid arthritis: frequency, predicting factors, natural history and outcome. RMD Open 2018;4:e000739. doi:10.1136/rmdopen-2018-000739
  • Carini, C., Hunter, E., Porter, D. et al. Chromosome conformation signatures define predictive markers of inadequate response to methotrexate in early rheumatoid arthritis. J Transl Med 16, 18 (2018) doi:10.1186/s12967-018-1387-9
  • Siebert, S. et al. Urinary proteomics can define distinct diagnostic inflammatory arthritis subgroups. Sci. Rep. 7, 40473; doi: 10.1038/srep40473 (2017).
  • Dale J, Paterson C, Tierney A, Ralston SH, Reid DM, Basu N, et al. The Scottish Early Rheumatoid Arthritis (SERA) Study: an inception cohort and biobank. BMC Musculoskelet Disord. 2016;17:461.
  • Kronisch C, McLernon DJ, Dale J, Paterson C, Ralston SH, Reid DM, et al. Brief report: predicting functional disability: one-year results from the scottish early rheumatoid arthritis inception cohort. Arthritis Rheumatol. 2016;68:1596–602.
  • Stalmach A, Johnsson H, McInnes IB, Husi H, Klein J, Dakna M, et al. (2014) Identification of Urinary Peptide Biomarkers Associated with Rheumatoid Arthritis. PLoS ONE 9(8): e104625. https://doi.org/10.1371/journal.pone.0104625
  1. Nijjar J, Morton FR, Bang H, Buckley CD, van der Heijde D , Gilmour A et al.   The impact of autoantibodies against citrullinated, carbamylated, and acetylated peptides on radiographic progression in patients with new-onset rheumatoid arthritis: an observational cohort study
  1. Hanlon, P. , Morton, F. , Siebert, S. , Jani, B. D. , Nicholl, B. I. , Lewsey, J. , McAllister, D.  and Mair, F. S.  (2022) Frailty in rheumatoid arthritis and its relationship with disease activity, hospitalisation and mortality: a longitudinal analysis of the Scottish Early Rheumatoid Arthritis cohort and UK Biobank. RMD Open, 8(1), e002111. (doi: 10.1136/rmdopen-2021-002111) (PMID:35292529) (PMCID:PMC8928366
  1. Claudio Carini, Ewan Hunter, Scottish Early Rheumatoid Arthritis Inception cohort Investigators, Aroul S. Ramadass, Jayne Green, Alexandre Akoulitchev, Iain B. McInnes and Carl S. Goodyear.  Chromosome conformation signatures define predictive markers of inadequate response to methotrexate in early rheumatoid arthritis. Carini et al. J Transl Med (2018) 16:18, https://doi.org/10.1186/s12967-018-1387-9
  1. James Dale , Caron Paterson, Ann Tierney, Stuart H. Ralston, David M. Reid, Neil Basu, John Harvie, Neil D. McKay, Sarah Saunders, Hilary Wilson, Robin Munro, Ruth Richmond, Derek Baxter, Michael McMahon, John McLaren, Vinod Kumar, Stefan Siebert, Iain McInnes and Duncan Porter. The Scottish Early Rheumatoid Arthritis (SERA) Study: an inception cohort and biobank. Dale et al. BMC Musculoskeletal Disorders (2016) 17:461, DOI 10.1186/s12891-016-1318-y
  1. George E Fragoulis, Caron Paterson, Ashley Gilmour, Mohammad H Derakhshan, Iain B McInnes, Duncan Porter, Stefan Siebert.  Neutropaenia in early rheumatoid arthritis: frequency, predicting factors, natural history and outcome.  RMD Open 2018;4:e000739. doi:10.1136/rmdopen-2018-000739.
  2. George E Fragoulis, Jonathan Cavanagh, Alistair Tindell, Mohammad Derakhshan, Caron Paterson, Duncan Porter Iain B McInnes, Stefan Siebert. Depression and anxiety in an early rheumatoid arthritis inception cohort. associations with demographic, socioeconomic and disease features. RMD Open 2020;6:e001376. doi:10.1136/rmdopen-2020-001376
  1. Jamie Robertson. Ph.D Thesis 2012.  The role of interleukin-6 in the metabolism of the apoB-containing lipoproteins in rheumatoid arthritis.
  1. Graeme J. M. Cowan, Katherine Miles, Lorenzo Capitani, Sophie S. B. Giguere, Hanna Johnsson, Carl Goodyear, Iain B. McInnes, on behalf of Scottish Early Rheumatoid Arthritis Inception Cohort Investigators, Steffen Breusch, David Gray and Mohini Gray.  (2020) In Human Autoimmunity, a Substantial Component of the B Cell Repertoire Consists of Polyclonal, Barely Mutated IgG+ve B Cells. Front. Immunol. 11:395. doi: 10.3389/fimmu.2020.00395
  1. Ping-Hsuan Hsieh, Claudia Geue, Olivia Wu, Emma McIntosh, Stefan Siebert. How Do Multiple Long-Term Conditions Impact on the Cost-of-Illness in Early Rheumatoid Arthritis? (Ref ?)
  1. Hanlon P, Morton F,Siebert S, et al. Frailty in Rheumatoid arthritis and its relationship with disease activity, hospitalisation and mortality: a longitudinal analysis of the Scottish Early Rheumatoid Arthritis cohort and UK Biobank. RMD Open 2022;8:e002111. doi:10.1136/rmdopen-2021-002111
  • Caroline Kronisch, David J. McLernon,  James Dale,  Caron Paterson,  Stuart H. Ralston,  David M. Reid, Ann Tierney,  John Harvie,  Neil McKay,  Hilary E. Wilson,  Robin Munro,  Sarah Saunders,  Ruth Richmond, Derek Baxter,  Mike McMahon,  Vinod Kumar, John McLaren, Stefan Siebert, Iain B. McInnes, Duncan Porter, Gary J. Macfarlane,  and Neil Basu.  Arthritis & Rheumatology, Vol. 68, No. 7, July 2016, pp 1596–1602, DOI 10.1002/art.39627
  • Jagtar S Nijjar, Fraser R Morton, Holger Bang, Christopher D Buckley, Désirée van der Heijde.  The impact of autoantibodies against citrullinated, carbamylated, and acetylated peptides on radiographic progression in patients with new-onset rheumatoid arthritis: an observational cohort study. Lancet Rheumatol. 2021 April 1; 3(4): e284–e293. doi:10.1016/S2665-9913(20)30381-7.
  • Pierre Redelinghuys, Lauren Whitehead, Andrea Augello, Rebecca A Drummond, Jean-Michel Levesque, Simon Vautier, Delyth M Reid1 Bernhard Kerscher,Julie A Taylor,1 Peter A Nigrovic, John Wright, Graeme I Murray, Janet A Willment, Lynne J Hocking, Maria J G Fernandes, Cosimo De Bari, Iain B Mcinnes, Gordon D Brown. MICL controls inflammation in rheumatoid arthritis.  Ann Rheum Dis 2016;75:1386–1391. (http://dx.doi.org/10.1136/annrheumdis-2014-206644).
  • Stefan Siebert, Duncan Porter, Caron Paterson, Rosie Hampson, Daniel Gaya,Agnieszka Latosinska, Harald Mischak, Joost Schanstra, William Mullen & Iain McInnes.  Urinary proteomics can definedistinct diagnostic inflammatory arthritis subgroups.  Sci. Rep. 7, 40473; doi: 10.1038/srep40473 (2017).
  • Gabrielle Simoneaua, Erica E. M. Moodiea, Jagtar S. Nijjarb, Robert W. Platta, and theScottish Early Rheumatoid Arthritis Inception Cohort Investigators. Estimating Optimal Dynamic Treatment Regimes With Survival Outcomes. Journal of the American Statistical Association 2020, VOL. 115, NO. 531, 1531-1539, https://doi.org/10.1080/01621459.2019.1629939
  • Stalmach A, Johnsson H, McInnes IB, Husi H, Klein J, et al. (2014) Identification of Urinary Peptide Biomarkers Associated with Rheumatoid Arthritis.  PLoS  ONE 9(8): e104625.  doi:10.1371/journal.pone.0104625
  • Genome-wide association study of response to methotrexate in early rheumatoid arthritis patients. Review Pharmacogenomics J. 2018 Jul;18(4):528-538. doi: 10.1038/s41397-018-0025-5. Epub 2018 May 25. PMID: 29795407 DOI: 10.1038/s41397-018-0025-5